منابع مشابه
ILC2s and fungal allergy
Innate lymphoid cells (ILCs) have emerged recently as an important component of the immune system and the cell type that regulates mucosal immune responses and tissue homeostasis. Group 2 ILCs (ILC2s), a subset of ILCs, reside in various tissues and are characterized by their capacity to produce type 2 cytokines and tissue growth factors. These ILC2s play an important role in allergic immune re...
متن کاملICOS regulates ILC2s in asthma
Asthma is a chronic inflammation of the airways leading to airway hyperreactivity and bronchoconstriction in response to allergens as well as unspecific stimuli such as cold air [1]. Classically, the key player cells in the pathogenesis of asthma are known to be T helper cells subsets including Th2, Th9 and Th17 as well as iNK T cells and dendritic cells [1-3]. An important aspect of the classi...
متن کاملThe Effects of Resistance Training on VCAM-1, ICAM-1 and CRP in Diabetic Rats
Objective: Many diabetic patients are susceptible to cardiovascular diseases which are known as one of the most important causes of mortality among diabetic patients. The aim of this study was to investigate the effects of eight weeks of resistance training on VCAM-1, ICAM-1 and CRP in diabetic rats. Materials and Methods: In this experimental study, 24 male Sprague- Dawley diabetic rats were ...
متن کاملICAM-1-Related Noncoding RNA in Cancer Stem Cells Maintains ICAM-1 Expression in Hepatocellular Carcinoma.
PURPOSE Portal vein tumor thrombus (PVTT) is a major complication of hepatocellular carcinoma (HCC) and is associated with poor survival. Long noncoding RNAs (lncRNA) contribute to HCC metastasis, but whether and how lncRNAs affect PVTT development remains unclear. In the present study, a novel highly expressed lncRNA (ICAM-1-related, ICR) was identified in ICAM-1(+)cancer stem cells (CSC) in H...
متن کاملCirculating forms of intercellular adhesion molecule (ICAM)-1 in mice lacking membranous ICAM-1.
Mice deficient in intercellular adhesion molecule-1 (ICAM-1), lacking membranous ICAM-1, show a normal development but abnormalities of inflammatory and immune functions. Although the membrane-bound form of ICAM-1 is not detectable in the mutant strain, circulating ICAM-1 (cICAM) is present in serum from ICAM-1-deficient mice in similar amounts as in serum from wild-type mice. These findings we...
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ژورنال
عنوان ژورنال: Nature Immunology
سال: 2018
ISSN: 1529-2908,1529-2916
DOI: 10.1038/s41590-018-0198-8